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Frequent upregulation of G9a promotes RelB-dependent proliferation and survival in multiple myeloma

BACKGROUND: Multiple myeloma is an incurable hematological malignancy characterized by a heterogeneous genetic and epigenetic landscape. Although a number of genetic aberrations associated with myeloma pathogenesis, progression and prognosis have been well characterized, the role of many epigenetic...

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Detalles Bibliográficos
Autores principales: Zhang, Xi Yun, Rajagopalan, Deepa, Chung, Tae-Hoon, Hooi, Lissa, Toh, Tan Boon, Tian, Johann Shane, Rashid, Masturah Bte Mohd Abdul, Sahib, Noor Rashidha Bte Meera, Gu, Mengjie, Lim, Jhin Jieh, Wang, Wilson, Chng, Wee Joo, Jha, Sudhakar, Chow, Edward Kai-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243326/
https://www.ncbi.nlm.nih.gov/pubmed/32477831
http://dx.doi.org/10.1186/s40164-020-00164-4