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Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients

INTRODUCTION: Antibiotic dosing in critically ill patients is challenging because their pharmacokinetics (PK) are altered and may change rapidly with disease progression. Standard dosing frequently leads to inadequate PK exposure. Therapeutic drug monitoring (TDM) offers a potential solution but req...

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Detalles Bibliográficos
Autores principales: Roggeveen, Luca F., Guo, Tingjie, Driessen, Ronald H., Fleuren, Lucas M., Thoral, Patrick, van der Voort, Peter H. J., Girbes, Armand R. J., Bosman, Rob J., Elbers, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243359/
https://www.ncbi.nlm.nih.gov/pubmed/32499697
http://dx.doi.org/10.3389/fphar.2020.00646