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Hydrophobic Drug/Toxin Binding Sites in Voltage-Dependent K(+) and Na(+) Channels
In the Na(v) channel family the lipophilic drugs/toxins binding sites and the presence of fenestrations in the channel pore wall are well defined and categorized. No such classification exists in the much larger K(v) channel family, although certain lipophilic compounds seem to deviate from binding...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243439/ https://www.ncbi.nlm.nih.gov/pubmed/32499709 http://dx.doi.org/10.3389/fphar.2020.00735 |