MiR-301a transcriptionally activated by HIF-2α promotes hypoxia-induced epithelial-mesenchymal transition by targeting TP63 in pancreatic cancer

BACKGROUND: Pancreatic cancer (PC) is one of the deadliest cancers worldwide. PC metastasis involves a complex set of events, including epithelial-mesenchymal transition (EMT), that increase tumor cell invasiveness. Recent evidence has shown that hypoxia is a major EMT regulator in pancreatic cancer...

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Detalles Bibliográficos
Autores principales: Zhang, Kun-Dong, Hu, Bin, Cen, Gang, Yang, Yu-Han, Chen, Wei-Wei, Guo, Zeng-Ya, Wang, Xiao-Feng, Zhao, Qian, Qiu, Zheng-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243651/
https://www.ncbi.nlm.nih.gov/pubmed/32476798
http://dx.doi.org/10.3748/wjg.v26.i19.2349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243651/
https://www.ncbi.nlm.nih.gov/pubmed/32476798
http://dx.doi.org/10.3748/wjg.v26.i19.2349

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