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3D Imaging of the Transparent Mycobacterium tuberculosis-Infected Lung Verifies the Localization of Innate Immune Cells With Granuloma

Using a novel tissue-clearing method, we aimed to visualize the three-dimensional (3D) distribution of immune cells within Mycobacterium tuberculosis (Mtb)-infected mice lungs. Ethyl cinnamate-based tissue clearing of Mtb-infected mice lungs was performed to obtain transparent lung samples, which we...

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Detalles Bibliográficos
Autores principales: Kang, Gyeong-Yi, Rhyu, Hyeong-Jun, Choi, Hong-Hee, Shin, Sung Jae, Hyun, Young-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243706/
https://www.ncbi.nlm.nih.gov/pubmed/32500041
http://dx.doi.org/10.3389/fcimb.2020.00226