The Lectin LecA Sensitizes the Human Stretch-Activated Channel TREK-1 but Not Piezo1 and Binds Selectively to Cardiac Non-myocytes

The healthy heart adapts continuously to a complex set of dynamically changing mechanical conditions. The mechanical environment is altered by, and contributes to, multiple cardiac diseases. Mechanical stimuli are detected and transduced by cellular mechano-sensors, including stretch-activated ion c...

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Detalles Bibliográficos
Autores principales: Darkow, Elisa, Rog-Zielinska, Eva A., Madl, Josef, Brandel, Annette, Siukstaite, Lina, Omidvar, Ramin, Kohl, Peter, Ravens, Ursula, Römer, Winfried, Peyronnet, Rémi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243936/
https://www.ncbi.nlm.nih.gov/pubmed/32499717
http://dx.doi.org/10.3389/fphys.2020.00457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243936/
https://www.ncbi.nlm.nih.gov/pubmed/32499717
http://dx.doi.org/10.3389/fphys.2020.00457

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