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PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation

PLAC1 (placenta enriched 1) is a mammalian trophoblast-specific protein. Aberrant expression of PLAC1 is observed in various human cancers, where it is involved in the motility, migration, and invasion of tumor cells, which are associated with the phosphoinositide 3-kinase (PI3K)/AKT pathway. We pre...

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Detalles Bibliográficos
Autores principales: Roldán, Diana Barea, Grimmler, Matthias, Hartmann, Christoph, Hubich-Rau, Stefanie, Beißert, Tim, Paret, Claudia, Cagna, Giuseppe, Rohde, Christoph, Wöll, Stefan, Koslowski, Michael, Türeci, Özlem, Sahin, Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244013/
https://www.ncbi.nlm.nih.gov/pubmed/32499871
http://dx.doi.org/10.18632/oncotarget.27582