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PLAC1 is essential for FGF7/FGFRIIIb-induced Akt-mediated cancer cell proliferation
PLAC1 (placenta enriched 1) is a mammalian trophoblast-specific protein. Aberrant expression of PLAC1 is observed in various human cancers, where it is involved in the motility, migration, and invasion of tumor cells, which are associated with the phosphoinositide 3-kinase (PI3K)/AKT pathway. We pre...
Autores principales: | Roldán, Diana Barea, Grimmler, Matthias, Hartmann, Christoph, Hubich-Rau, Stefanie, Beißert, Tim, Paret, Claudia, Cagna, Giuseppe, Rohde, Christoph, Wöll, Stefan, Koslowski, Michael, Türeci, Özlem, Sahin, Ugur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244013/ https://www.ncbi.nlm.nih.gov/pubmed/32499871 http://dx.doi.org/10.18632/oncotarget.27582 |
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