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Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma

The paternally imprinted neuronatin (NNAT) gene has been identified as a target of aberrant epigenetic silencing in diverse cancers, but no association with pediatric bone cancers has been reported to date. In screening childhood cancers, we identified aberrant CpG island hypermethylation in a major...

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Detalles Bibliográficos
Autores principales: Saeed, Haleema, Sinha, Sayantani, Mella, Christine, Kuerbitz, Jeffrey S., Cales, Monica L., Steele, Mark A., Stanke, Jennifer, Damron, Derek, Safadi, Fayez, Kuerbitz, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244018/
https://www.ncbi.nlm.nih.gov/pubmed/32499872
http://dx.doi.org/10.18632/oncotarget.27583