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The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma

Acyl-CoA ligase 4 (ACSL4) has been reported to be overexpressed in hepatocellular carcinoma (HCC) and to enhance cell proliferation. However, the molecular mechanisms underlying the role of ACSL4 in HCC progression remain largely unclear. Here, we aimed to investigate whether and how O-GlcNAcylation...

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Detalles Bibliográficos
Autores principales: Wang, Jiachen, Wang, Zhao, Yuan, Jiaxiang, Wang, Jiaxiang, Shen, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244051/
https://www.ncbi.nlm.nih.gov/pubmed/32357142
http://dx.doi.org/10.18632/aging.103092