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Lycopene prevents carcinogen-induced cutaneous tumor by enhancing activation of the Nrf2 pathway through p62-triggered autophagic Keap1 degradation

Biologically active natural products have been used for the chemoprevention of cutaneous tumors. Lycopene is the main active phytochemical in tomatoes. We herein aimed to assess the cancer preventive effects of lycopene and to find potential molecular targets. In chemically-induced cutaneous tumor m...

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Detalles Bibliográficos
Autores principales: Wang, Siliang, Wu, Yuan-Yuan, Wang, Xu, Shen, Peiliang, Jia, Qi, Yu, Suyun, Wang, Yuan, Li, Xiaoman, Chen, Wenxing, Wang, Aiyun, Lu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244072/
https://www.ncbi.nlm.nih.gov/pubmed/32365333
http://dx.doi.org/10.18632/aging.103132