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Urinary metabolites associate with the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease

BACKGROUND: The variable course of autosomal dominant polycystic kidney disease (ADPKD), and the advent of renoprotective treatment require early risk stratification. We applied urinary metabolomics to explore differences associated with estimated glomerular filtration rate (eGFR; CKD-EPI equation)...

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Detalles Bibliográficos
Autores principales: Dekker, Shosha E. I., Verhoeven, Aswin, Soonawala, Darius, Peters, Dorien J. M., de Fijter, Johan W., Mayboroda, Oleg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244119/
https://www.ncbi.nlm.nih.gov/pubmed/32442208
http://dx.doi.org/10.1371/journal.pone.0233213