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Comparative glycosylation mapping of plasma-derived and recombinant human factor VIII

Human coagulation factor VIII (FVIII) is a key co-factor in the clotting cascade, the deficiency of which leads to Hemophilia A. Human plasma-derived (pdFVIII) and recombinant FVIII (rFVIII) had been used as effective products to prevent and treat bleeding episodes. Both FVIII products share identic...

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Detalles Bibliográficos
Autores principales: Qu, Jingyao, Ma, Cheng, Xu, Xiao-Qian, Xiao, Min, Zhang, Junping, Li, Dong, Liu, Ding, Konkle, Barbara A., Miao, Carol H., Li, Lei, Xiao, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244179/
https://www.ncbi.nlm.nih.gov/pubmed/32442215
http://dx.doi.org/10.1371/journal.pone.0233576