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Frequency-Dependent Block of Excitatory Neurotransmission by Isoflurane via Dual Presynaptic Mechanisms

Volatile anesthetics are widely used for surgery, but neuronal mechanisms of anesthesia remain unidentified. At the calyx of Held in brainstem slices from rats of either sex, isoflurane at clinical doses attenuated EPSCs by decreasing the release probability and the number of readily releasable vesi...

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Detalles Bibliográficos
Autores principales: Wang, Han-Ying, Eguchi, Kohgaku, Yamashita, Takayuki, Takahashi, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244188/
https://www.ncbi.nlm.nih.gov/pubmed/32327530
http://dx.doi.org/10.1523/JNEUROSCI.2946-19.2020