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Combinatorial screening of biochemical and physical signals for phenotypic regulation of stem cell–based cartilage tissue engineering

Despite great progress in biomaterial design strategies for replacing damaged articular cartilage, prevention of stem cell-derived chondrocyte hypertrophy and resulting inferior tissue formation is still a critical challenge. Here, by using engineered biomaterials and a high-throughput system for sc...

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Detalles Bibliográficos
Autores principales: Lee, Junmin, Jeon, Oju, Kong, Ming, Abdeen, Amr A., Shin, Jung-Youn, Lee, Ha Neul, Lee, Yu Bin, Sun, Wujin, Bandaru, Praveen, Alt, Daniel S., Lee, KangJu, Kim, Han-Jun, Lee, Sang Jin, Chaterji, Somali, Shin, Su Ryon, Alsberg, Eben, Khademhosseini, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244269/
https://www.ncbi.nlm.nih.gov/pubmed/32494742
http://dx.doi.org/10.1126/sciadv.aaz5913