Beta‐blockers withdrawal in patients with heart failure with preserved ejection fraction and chronotropic incompetence: Effect on functional capacity rationale and study design of a prospective, randomized, controlled trial (The Preserve‐HR trial)

BACKGROUND: The pathophysiology of heart failure with preserved ejection fraction (HFpEF) is complex and multifactorial. Chronotropic incompetence (ChI) has emerged as a crucial pathophysiological mechanism. Beta‐blockers, drugs with negative chronotropic effects, are commonly used in HFpEF, althoug...

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Detalles Bibliográficos
Autores principales: Palau, Patricia, Seller, Julia, Domínguez, Eloy, Gómez, Inés, Ramón, José María, Sastre, Clara, de la Espriella, Rafael, Santas, Enrique, Miñana, Gema, Chorro, Francisco J., González‐Juanatey, José Ramón, Núñez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2020
Materias:
Trial Designs
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244302/
https://www.ncbi.nlm.nih.gov/pubmed/32073676
http://dx.doi.org/10.1002/clc.23345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244302/
https://www.ncbi.nlm.nih.gov/pubmed/32073676
http://dx.doi.org/10.1002/clc.23345

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