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Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders

Activation of the innate immune system is commonly associated with depression. Immunomodulatory drugs may have efficacy for depressive symptoms that are co-morbidly associated with inflammatory disorders. We report a large-scale re-analysis by standardized procedures (mega-analysis) of patient-level...

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Detalles Bibliográficos
Autores principales: Wittenberg, Gayle M., Stylianou, Annie, Zhang, Yun, Sun, Yu, Gupta, Ashutosh, Jagannatha, P. S., Wang, Dai, Hsu, Benjamin, Curran, Mark E., Khan, Shahid, Chen, Guang, Bullmore, Edward T., Drevets, Wayne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244402/
https://www.ncbi.nlm.nih.gov/pubmed/31427751
http://dx.doi.org/10.1038/s41380-019-0471-8