Surrogate endpoints for overall survival in randomised controlled trials of localised osteosarcoma: A meta-analytic evaluation

Event-free survival (EFS) is considered the most reliable surrogate endpoint for overall survival (OS) in randomised controlled trials (RCTs) of adjuvant therapies for malignant tumours. However, the surrogacy of intermediate endpoints such as EFS for OS in trials of patients with osteosarcoma has n...

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Detalles Bibliográficos
Autores principales: Tanaka, Kazuhiro, Kawano, Masanori, Iwasaki, Tatsuya, Matsuda, Shogo, Itonaga, Ichiro, Tsumura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244479/
https://www.ncbi.nlm.nih.gov/pubmed/32444660
http://dx.doi.org/10.1038/s41598-020-65591-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244479/
https://www.ncbi.nlm.nih.gov/pubmed/32444660
http://dx.doi.org/10.1038/s41598-020-65591-z

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