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Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C

The PI3K/Akt pathway promotes skeletal muscle growth and myogenic differentiation. Although its importance in skeletal muscle biology is well documented, many of its substrates remain to be identified. We here studied PI3K/Akt signaling in contracting skeletal muscle cells by quantitative phosphopro...

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Detalles Bibliográficos
Autores principales: Reimann, Lena, Schwäble, Anja N., Fricke, Anna L., Mühlhäuser, Wignand W. D., Leber, Yvonne, Lohanadan, Keerthika, Puchinger, Martin G., Schäuble, Sascha, Faessler, Erik, Wiese, Heike, Reichenbach, Christa, Knapp, Bettina, Peikert, Christian D., Drepper, Friedel, Hahn, Udo, Kreutz, Clemens, van der Ven, Peter F. M., Radziwill, Gerald, Djinović-Carugo, Kristina, Fürst, Dieter O., Warscheid, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244511/
https://www.ncbi.nlm.nih.gov/pubmed/32444788
http://dx.doi.org/10.1038/s42003-020-0982-5