Kinesin-14 motors drive a right-handed helical motion of antiparallel microtubules around each other

Within the mitotic spindle, kinesin motors cross-link and slide overlapping microtubules. Some of these motors exhibit off-axis power strokes, but their impact on motility and force generation in microtubule overlaps has not been investigated. Here, we develop and utilize a three-dimensional in vitr...

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Detalles Bibliográficos
Autores principales: Mitra, Aniruddha, Meißner, Laura, Gandhimathi, Rojapriyadharshini, Renger, Roman, Ruhnow, Felix, Diez, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244531/
https://www.ncbi.nlm.nih.gov/pubmed/32444784
http://dx.doi.org/10.1038/s41467-020-16328-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244531/
https://www.ncbi.nlm.nih.gov/pubmed/32444784
http://dx.doi.org/10.1038/s41467-020-16328-z

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