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Kinesin-14 motors drive a right-handed helical motion of antiparallel microtubules around each other
Within the mitotic spindle, kinesin motors cross-link and slide overlapping microtubules. Some of these motors exhibit off-axis power strokes, but their impact on motility and force generation in microtubule overlaps has not been investigated. Here, we develop and utilize a three-dimensional in vitr...
Autores principales: | Mitra, Aniruddha, Meißner, Laura, Gandhimathi, Rojapriyadharshini, Renger, Roman, Ruhnow, Felix, Diez, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244531/ https://www.ncbi.nlm.nih.gov/pubmed/32444784 http://dx.doi.org/10.1038/s41467-020-16328-z |
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