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KLOTHO polymorphisms and age-related outcomes in community-dwelling older subjects: The São Paulo Ageing & Health (SPAH) Study

Defective KLOTHO gene expression in mice led to a syndrome resembling human ageing. This study evaluated three KLOTHO polymorphisms, namely G395A, C1818T, and C370S, in an elderly population (mean age of 73 years) and their associations with ageing-related outcomes (cardiovascular events, kidney fun...

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Detalles Bibliográficos
Autores principales: Pereira, Rosa Maria R., Freitas, Thiago Quadrante, Franco, André Silva, Takayama, Liliam, Caparbo, Valeria F., Domiciano, Diogo S., Machado, Luana G., Figueiredo, Camille P., Menezes, Paulo R., Onuchic, Luiz Fernando, de Castro, Isac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244540/
https://www.ncbi.nlm.nih.gov/pubmed/32444684
http://dx.doi.org/10.1038/s41598-020-65441-y