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KLOTHO polymorphisms and age-related outcomes in community-dwelling older subjects: The São Paulo Ageing & Health (SPAH) Study
Defective KLOTHO gene expression in mice led to a syndrome resembling human ageing. This study evaluated three KLOTHO polymorphisms, namely G395A, C1818T, and C370S, in an elderly population (mean age of 73 years) and their associations with ageing-related outcomes (cardiovascular events, kidney fun...
Autores principales: | Pereira, Rosa Maria R., Freitas, Thiago Quadrante, Franco, André Silva, Takayama, Liliam, Caparbo, Valeria F., Domiciano, Diogo S., Machado, Luana G., Figueiredo, Camille P., Menezes, Paulo R., Onuchic, Luiz Fernando, de Castro, Isac |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244540/ https://www.ncbi.nlm.nih.gov/pubmed/32444684 http://dx.doi.org/10.1038/s41598-020-65441-y |
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