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Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine

The small intestine has a robust regenerative capacity, and various cell types serve as “cells-of-origin” in the epithelial regeneration process after injury. However, how much each population contributes to regeneration remains unclear. Using lineage tracing, we found that Lgr5-expressing cell deri...

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Detalles Bibliográficos
Autores principales: Sato, Taku, Sase, Miwako, Ishikawa, Shun, Kajita, Mihoko, Asano, Jumpei, Sato, Toshiro, Mori, Yoshiyuki, Ohteki, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244543/
https://www.ncbi.nlm.nih.gov/pubmed/32444673
http://dx.doi.org/10.1038/s41598-020-64987-1