N(6)-methyladenosine regulates glycolysis of cancer cells through PDK4

Studies on biological functions of N(6)-methyladenosine (m(6)A) modification in mRNA have sprung up in recent years. We find m(6)A can positively regulate the glycolysis of cancer cells. Specifically, m(6)A-sequencing and functional studies confirm that pyruvate dehydrogenase kinase 4 (PDK4) is invo...

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Detalles Bibliográficos
Autores principales: Li, Zihan, Peng, Yanxi, Li, Jiexin, Chen, Zhuojia, Chen, Feng, Tu, Jian, Lin, Shuibin, Wang, Hongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244544/
https://www.ncbi.nlm.nih.gov/pubmed/32444598
http://dx.doi.org/10.1038/s41467-020-16306-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244544/
https://www.ncbi.nlm.nih.gov/pubmed/32444598
http://dx.doi.org/10.1038/s41467-020-16306-5

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