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N(6)-methyladenosine regulates glycolysis of cancer cells through PDK4

Studies on biological functions of N(6)-methyladenosine (m(6)A) modification in mRNA have sprung up in recent years. We find m(6)A can positively regulate the glycolysis of cancer cells. Specifically, m(6)A-sequencing and functional studies confirm that pyruvate dehydrogenase kinase 4 (PDK4) is invo...

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Detalles Bibliográficos
Autores principales:	Li, Zihan, Peng, Yanxi, Li, Jiexin, Chen, Zhuojia, Chen, Feng, Tu, Jian, Lin, Shuibin, Wang, Hongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244544/ https://www.ncbi.nlm.nih.gov/pubmed/32444598 http://dx.doi.org/10.1038/s41467-020-16306-5

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