GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer

TERT promoter mutations occur in the majority of glioblastoma, bladder cancer (BC), and other malignancies while the ETS family transcription factors GABPA and its partner GABPB1 activate the mutant TERT promoter and telomerase in these tumors. GABPA depletion or the disruption of the GABPA/GABPB1 c...

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Detalles Bibliográficos
Autores principales: Guo, Yanxia, Yuan, Xiaotian, Li, Kailin, Dai, Mingkai, Zhang, Lu, Wu, Yujiao, Sun, Chao, Chen, Yuan, Cheng, Guanghui, Liu, Cheng, Strååt, Klas, Kong, Feng, Zhao, Shengtian, Bjorkhölm, Magnus, Xu, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244562/
https://www.ncbi.nlm.nih.gov/pubmed/31802036
http://dx.doi.org/10.1038/s41418-019-0466-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244562/
https://www.ncbi.nlm.nih.gov/pubmed/31802036
http://dx.doi.org/10.1038/s41418-019-0466-7

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