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Dexmedetomidine had neuroprotective effects on hippocampal neuronal cells via targeting lncRNA SHNG16 mediated microRNA-10b-5p/BDNF axis

Dexmedetomidine (DEX), a highly selective alpha2 adrenergic receptor agonist, is a commonly used anesthetic drug in surgical procedures. Previous studies have indicated that DEX exerts neuroprotective effects while the detailed mechanism has not been fully elucidated. Here, we aim to study the role...

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Detalles Bibliográficos
Autores principales: Wang, Li, Liu, Weihua, Zhang, Yanjun, Hu, Zhanfei, Guo, Hao, Lv, Jingshu, Du, Hongyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244615/
https://www.ncbi.nlm.nih.gov/pubmed/32323054
http://dx.doi.org/10.1007/s11010-020-03726-6