Citarinostat and Momelotinib co-target HDAC6 and JAK2/STAT3 in lymphoid malignant cell lines: a potential new therapeutic combination

Histone deacetylase (HDAC) inhibitors represent an encouraging class of antitumor drugs. HDAC inhibitors induce a series of molecular and biological responses and minimal toxicity to normal cells. Citarinostat (Acy-241) is a second generation, orally administered, HDAC6-selective inhibitor. Momeloti...

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Detalles Bibliográficos
Autores principales: Cosenza, Maria, Civallero, Monica, Marcheselli, Luigi, Sacchi, Stefano, Pozzi, Samantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244621/
https://www.ncbi.nlm.nih.gov/pubmed/32394008
http://dx.doi.org/10.1007/s10495-020-01607-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244621/
https://www.ncbi.nlm.nih.gov/pubmed/32394008
http://dx.doi.org/10.1007/s10495-020-01607-3

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