The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson’s disease, multiple system atrophy and dementia with Lewy bodies

Synucleinopathies, such as Parkinson’s disease (PD), multiple system atrophy (MSA), and dementia with Lewy bodies (DLB), are defined by the presence of α-synuclein (αSYN) aggregates throughout the nervous system but diverge from one another with regard to their clinical and pathological phenotype. T...

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Detalles Bibliográficos
Autores principales: Van der Perren, Anke, Gelders, Géraldine, Fenyi, Alexis, Bousset, Luc, Brito, Filipa, Peelaerts, Wouter, Van den Haute, Chris, Gentleman, Steve, Melki, Ronald, Baekelandt, Veerle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244622/
https://www.ncbi.nlm.nih.gov/pubmed/32356200
http://dx.doi.org/10.1007/s00401-020-02157-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244622/
https://www.ncbi.nlm.nih.gov/pubmed/32356200
http://dx.doi.org/10.1007/s00401-020-02157-3

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