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SNHG7 is a lncRNA oncogene controlled by Insulin-like Growth Factor signaling through a negative feedback loop to tightly regulate proliferation

Evidence suggests Insulin-like growth factor 1 (IGF1) signaling is involved in the initiation and progression of a subset of breast cancers by inducing cell proliferation and survival. Although the signaling cascade following IGF1 receptor activation is well-studied, the key elements of the transcri...

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Detalles Bibliográficos
Autores principales: Boone, David N., Warburton, Andrew, Som, Sreeroopa, Lee, Adrian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244715/
https://www.ncbi.nlm.nih.gov/pubmed/32444795
http://dx.doi.org/10.1038/s41598-020-65109-7