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The role of the microbiome and psychosocial stress in the expression and activity of drug metabolizing enzymes in mice

The gut microbiota is involved in a number of different metabolic processes of the host organism, including the metabolism of xenobiotics. In our study, we focused on liver cytochromes P450 (CYPs), which can metabolize a wide range of exo- and endogenous molecules. We studied changes in mRNA express...

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Detalles Bibliográficos
Autores principales: Zemanová, Nina, Anzenbacher, Pavel, Zapletalová, Iveta, Jourová, Lenka, Hermanová, Petra, Hudcovic, Tomáš, Kozáková, Hana, Vodička, Martin, Pácha, Jiří, Anzenbacherová, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244717/
https://www.ncbi.nlm.nih.gov/pubmed/32444678
http://dx.doi.org/10.1038/s41598-020-65595-9