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The role of the microbiome and psychosocial stress in the expression and activity of drug metabolizing enzymes in mice
The gut microbiota is involved in a number of different metabolic processes of the host organism, including the metabolism of xenobiotics. In our study, we focused on liver cytochromes P450 (CYPs), which can metabolize a wide range of exo- and endogenous molecules. We studied changes in mRNA express...
Autores principales: | Zemanová, Nina, Anzenbacher, Pavel, Zapletalová, Iveta, Jourová, Lenka, Hermanová, Petra, Hudcovic, Tomáš, Kozáková, Hana, Vodička, Martin, Pácha, Jiří, Anzenbacherová, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244717/ https://www.ncbi.nlm.nih.gov/pubmed/32444678 http://dx.doi.org/10.1038/s41598-020-65595-9 |
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