Genetic switches designed for eukaryotic cells and controlled by serine integrases

Recently, new serine integrases have been identified, increasing the possibility of scaling up genomic modulation tools. Here, we describe the use of unidirectional genetic switches to evaluate the functionality of six serine integrases in different eukaryotic systems: the HEK 293T cell lineage, bov...

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Detalles Bibliográficos
Autores principales: Gomide, Mayna S., Sales, Thais T., Barros, Luciana R. C., Limia, Cintia G., de Oliveira, Marco A., Florentino, Lilian H., Barros, Leila M. G., Robledo, Maria L., José, Gustavo P. C., Almeida, Mariana S. M., Lima, Rayane N., Rehen, Stevens K., Lacorte, Cristiano, Melo, Eduardo O., Murad, André M., Bonamino, Martín H., Coelho, Cintia M., Rech, Elibio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244727/
https://www.ncbi.nlm.nih.gov/pubmed/32444777
http://dx.doi.org/10.1038/s42003-020-0971-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244727/
https://www.ncbi.nlm.nih.gov/pubmed/32444777
http://dx.doi.org/10.1038/s42003-020-0971-8

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