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Methylation of a CGATA element inhibits binding and regulation by GATA-1
Alterations in DNA methylation occur during development, but the mechanisms by which they influence gene expression remain uncertain. There are few examples where modification of a single CpG dinucleotide directly affects transcription factor binding and regulation of a target gene in vivo. Here, we...
Autores principales: | Yang, Lu, Chen, Zhiliang, Stout, Elizabeth S., Delerue, Fabien, Ittner, Lars M., Wilkins, Marc R., Quinlan, Kate G. R., Crossley, Merlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244756/ https://www.ncbi.nlm.nih.gov/pubmed/32444652 http://dx.doi.org/10.1038/s41467-020-16388-1 |
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