Transcriptional activation during cell reprogramming correlates with the formation of 3D open chromatin hubs

Chromosome structure is a crucial regulatory factor for a wide range of nuclear processes. Chromosome conformation capture (3C)-based experiments combined with computational modelling are pivotal for unveiling 3D chromosome structure. Here, we introduce TADdyn, a tool that integrates time-course 3C...

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Detalles Bibliográficos
Autores principales: Di Stefano, Marco, Stadhouders, Ralph, Farabella, Irene, Castillo, David, Serra, François, Graf, Thomas, Marti-Renom, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244774/
https://www.ncbi.nlm.nih.gov/pubmed/32444798
http://dx.doi.org/10.1038/s41467-020-16396-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244774/
https://www.ncbi.nlm.nih.gov/pubmed/32444798
http://dx.doi.org/10.1038/s41467-020-16396-1

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