Successful Regulatory T Cell-Based Therapy Relies on Inhibition of T Cell Effector Function and Enrichment of FOXP3+ Cells in a Humanized Mouse Model of Skin Inflammation

BACKGROUND: Recent clinical trials using regulatory T cells (Treg) support the therapeutic potential of Treg-based therapy in transplantation and autoinflammatory diseases. Despite these clinical successes, the effect of Treg on inflamed tissues, as well as their impact on immune effector function i...

Descripción completa

Detalles Bibliográficos
Autores principales: Landman, S., de Oliveira, V. L., Peppelman, M., Fasse, E., van Rijssen, E., Bauland, S. C., van Erp, P., Joosten, I., Koenen, H. J. P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244960/
https://www.ncbi.nlm.nih.gov/pubmed/32509883
http://dx.doi.org/10.1155/2020/7680131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244960/
https://www.ncbi.nlm.nih.gov/pubmed/32509883
http://dx.doi.org/10.1155/2020/7680131

Ejemplares similares