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Successful Regulatory T Cell-Based Therapy Relies on Inhibition of T Cell Effector Function and Enrichment of FOXP3+ Cells in a Humanized Mouse Model of Skin Inflammation

BACKGROUND: Recent clinical trials using regulatory T cells (Treg) support the therapeutic potential of Treg-based therapy in transplantation and autoinflammatory diseases. Despite these clinical successes, the effect of Treg on inflamed tissues, as well as their impact on immune effector function i...

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Detalles Bibliográficos
Autores principales:	Landman, S., de Oliveira, V. L., Peppelman, M., Fasse, E., van Rijssen, E., Bauland, S. C., van Erp, P., Joosten, I., Koenen, H. J. P. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244960/ https://www.ncbi.nlm.nih.gov/pubmed/32509883 http://dx.doi.org/10.1155/2020/7680131

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