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Klotho Alleviates Lung Injury Caused by Paraquat via Suppressing ROS/P38 MAPK-Regulated Inflammatory Responses and Apoptosis

Acute lung injury (ALI) induced by paraquat (PQ) progresses rapidly with high mortality; however, there is no effective treatment, and the specific mechanism is not well understood. The antiaging protein klotho (KL) has multiple functions and exerts significant influences on various pathophysiologic...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiqiang, Nian, Qing, Chen, Gang, Cui, Shuqing, Han, Yuzhen, Zhang, Jinying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244968/
https://www.ncbi.nlm.nih.gov/pubmed/32509139
http://dx.doi.org/10.1155/2020/1854206