Inhibiting the Progression of Human Retinoblastoma Cell by Downregulation of MMP-2/MMP-9 Using Short Hairpin RNAs (shRNAs) In Vitro

OBJECTIVE: To investigate the effect of downregulated matrix metalloproteinases (MMPs) gene on the proliferation, apoptosis, cell cycle, migration, and invasion of human retinoblastoma (RB) cell line in vitro. METHODS: Small hairpin RNA (shRNA) targeting MMP-2/MMP-9 was designed and transfected into...

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Detalles Bibliográficos
Autores principales: Meng, Nana, Zhao, Zhi, Shi, Chunhe, Xia, Leizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244976/
https://www.ncbi.nlm.nih.gov/pubmed/32509341
http://dx.doi.org/10.1155/2020/4912347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244976/
https://www.ncbi.nlm.nih.gov/pubmed/32509341
http://dx.doi.org/10.1155/2020/4912347

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