Apatinib, a Novel Tyrosine Kinase Inhibitor, Promotes ROS-Dependent Apoptosis and Autophagy via the Nrf2/HO-1 Pathway in Ovarian Cancer Cells

Apatinib, a new-generation oral tyrosine kinase inhibitor targeting the vascular endothelial growth factor receptor 2 (VEGFR2) signaling pathway, shows favorable therapeutic effects in various malignant tumors. However, its effect on ovarian cancer has not yet been characterized. Here, we demonstrat...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Xiaodan, Li, Ji, Li, Yizhuo, Wang, Shouhan, Li, Qingchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244982/
https://www.ncbi.nlm.nih.gov/pubmed/32509141
http://dx.doi.org/10.1155/2020/3145182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244982/
https://www.ncbi.nlm.nih.gov/pubmed/32509141
http://dx.doi.org/10.1155/2020/3145182

Ejemplares similares