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Apatinib, a Novel Tyrosine Kinase Inhibitor, Promotes ROS-Dependent Apoptosis and Autophagy via the Nrf2/HO-1 Pathway in Ovarian Cancer Cells

Apatinib, a new-generation oral tyrosine kinase inhibitor targeting the vascular endothelial growth factor receptor 2 (VEGFR2) signaling pathway, shows favorable therapeutic effects in various malignant tumors. However, its effect on ovarian cancer has not yet been characterized. Here, we demonstrat...

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Detalles Bibliográficos
Autores principales:	Sun, Xiaodan, Li, Ji, Li, Yizhuo, Wang, Shouhan, Li, Qingchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244982/ https://www.ncbi.nlm.nih.gov/pubmed/32509141 http://dx.doi.org/10.1155/2020/3145182

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