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Oligonucleotide conjugated antibodies permit highly multiplexed immunofluorescence for future use in clinical histopathology

Significance: Advanced genetic characterization has informed cancer heterogeneity and the challenge it poses to effective therapy; however, current methods lack spatial context, which is vital to successful cancer therapy. Conventional immunolabeling, commonplace in the clinic, can provide spatial c...

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Detalles Bibliográficos
Autores principales: McMahon, Nathan P., Jones, Jocelyn A., Kwon, Sunjong, Chin, Koei, Nederlof, Michel A., Gray, Joe W., Gibbs, Summer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245007/
https://www.ncbi.nlm.nih.gov/pubmed/32445299
http://dx.doi.org/10.1117/1.JBO.25.5.056004