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Context-aware seeds for read mapping

MOTIVATION: Most modern seed-and-extend NGS read mappers employ a seeding scheme that requires extracting t non-overlapping seeds in each read in order to find all valid mappings under an edit distance threshold of t. As t grows, this seeding scheme forces mappers to use more and shorter seeds, whic...

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Detalles Bibliográficos
Autores principales: Xin, Hongyi, Shao, Mingfu, Kingsford, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245042/
https://www.ncbi.nlm.nih.gov/pubmed/32489399
http://dx.doi.org/10.1186/s13015-020-00172-3