Protective Effects of Crocetin on Arsenic Trioxide-Induced Hepatic Injury: Involvement of Suppression in Oxidative Stress and Inflammation Through Activation of Nrf2 Signaling Pathway in Rats

PURPOSE: Arsenic trioxide (ATO) has been shown to induce hepatic injury. Crocetin is a primary constituent of saffron, which has been verified to have antioxidant and anti-inflammatory effects. In the current experiment, we evaluated the efficacy of crocetin against ATO-induced hepatic injury and ex...

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Detalles Bibliográficos
Autores principales: Liu, Yanshuang, Liang, Yingran, Zheng, Bin, Chu, Li, Ma, Donglai, Wang, Hongfang, Chu, Xi, Zhang, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245440/
https://www.ncbi.nlm.nih.gov/pubmed/32546959
http://dx.doi.org/10.2147/DDDT.S247947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245440/
https://www.ncbi.nlm.nih.gov/pubmed/32546959
http://dx.doi.org/10.2147/DDDT.S247947

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