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KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats

OBJECTIVE: The present study focused on the development of a poloxamer 407 thermosensitive hydrogel loaded with keratinocyte growth factor-2 (KGF-2) and fibroblast growth factor-21 (FGF-21) as a therapeutic biomaterial in a scald-wound model of type-2 diabetes in Goto-Kakizaki (GK) rats. RESEARCH DE...

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Detalles Bibliográficos
Autores principales: Yang, Xuanxin, Yang, Rongshuai, Chen, Min, Zhou, Qingde, Zheng, Yingying, Lu, Chao, Bi, Jianing, Sun, Wenzhe, Huang, Tongzhou, Li, Lijia, Gong, Jianxiang, Li, Xiaokun, Hui, Qi, Wang, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245451/
https://www.ncbi.nlm.nih.gov/pubmed/32434772
http://dx.doi.org/10.1136/bmjdrc-2019-001009