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Enhanced Percutaneous Delivery of Methotrexate Using Micelles Prepared with Novel Cationic Amphipathic Material

BACKGROUND: Methotrexate (MTX) is an antiproliferative drug widely used to treat inflammatory diseases and autoimmune diseases. The application of percutaneous administration is hindered due to its poor transdermal penetration. To reduce side effects and enhanced percutaneous delivery of MTX, novel...

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Detalles Bibliográficos
Autores principales: Zhao, Yun-Chun, Zheng, Hai-Li, Wang, Xiao-Rong, Zheng, Xiao-Ling, Chen, Yue, Fei, Wei-Dong, Zheng, Yong-Quan, Wang, Wen-Xi, Zheng, Cai-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245457/
https://www.ncbi.nlm.nih.gov/pubmed/32547012
http://dx.doi.org/10.2147/IJN.S251431