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Enhanced Percutaneous Delivery of Methotrexate Using Micelles Prepared with Novel Cationic Amphipathic Material
BACKGROUND: Methotrexate (MTX) is an antiproliferative drug widely used to treat inflammatory diseases and autoimmune diseases. The application of percutaneous administration is hindered due to its poor transdermal penetration. To reduce side effects and enhanced percutaneous delivery of MTX, novel...
Autores principales: | Zhao, Yun-Chun, Zheng, Hai-Li, Wang, Xiao-Rong, Zheng, Xiao-Ling, Chen, Yue, Fei, Wei-Dong, Zheng, Yong-Quan, Wang, Wen-Xi, Zheng, Cai-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245457/ https://www.ncbi.nlm.nih.gov/pubmed/32547012 http://dx.doi.org/10.2147/IJN.S251431 |
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