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Improved Antitumor Outcomes for Colon Cancer Using Nanomicelles Loaded with the Novel Antitumor Agent LA67

BACKGROUND: LA67 is a derivative of triptolide that exhibits strong antitumor activity. This derivative has a better safety profile than triptolide, but is limited by poor aqueous solubility. AIM AND METHODS: To improve solubility and further increase therapeutic efficacy, we prepared LA67-loaded po...

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Detalles Bibliográficos
Autores principales: Cui, Minhu, Jin, Mingji, Han, Mingfeng, Zang, Yingda, Li, Chuangjun, Zhang, Dongming, Huang, Wei, Gao, Zhonggao, Yin, Xuezhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245463/
https://www.ncbi.nlm.nih.gov/pubmed/32547014
http://dx.doi.org/10.2147/IJN.S241577