Inhibition of ubiquitin-specific protease 7 sensitizes acute myeloid leukemia to chemotherapy

Resistance of acute myeloid leukemia (AML) to therapeutic agents is frequent. Consequently, the mechanisms leading to this resistance must be understood and addressed. In this paper, we demonstrate that inhibition of deubiquitinylase USP7 significantly reduces cell proliferation in vitro and in vivo...

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Detalles Bibliográficos
Autores principales: Cartel, Maëlle, Mouchel, Pierre-Luc, Gotanègre, Mathilde, David, Laure, Bertoli, Sarah, Mansat-De Mas, Véronique, Besson, Arnaud, Sarry, Jean-Emmanuel, Manenti, Stéphane, Didier, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245510/
https://www.ncbi.nlm.nih.gov/pubmed/32447346
http://dx.doi.org/10.1038/s41375-020-0878-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245510/
https://www.ncbi.nlm.nih.gov/pubmed/32447346
http://dx.doi.org/10.1038/s41375-020-0878-x

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